Lung Cancer Biomarker Testing ECHO

May 2021

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February 2022

Orientation to the Comprehensive Lung Cancer Biomarker Testing ECHO Series

This session provided an overview of the ECHO model, along with providing a data level-set of the current burden of lung cancer in each state, and provide a brief introduction to lung cancer biomarker testing, including the current guidelines and approved FDA biomarker-driven treatments.

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Lung Cancer Biomarker Testing ECHO – Georgia – 6-9-2021 – Recording

Lung Cancer Biomarker Testing ECHO – Georgia – 6-9-2021 – Slides

Lung Cancer Biomarker Testing ECHO – Kentucky – 5-27-2021 – Recording

Lung Cancer Biomarker Testing ECHO – Kentucky – 5-27-2021 – Slides

Lung Cancer Biomarker Testing ECHO – Mississippi – 5-25-2021 – Recording

Lung Cancer Biomarker Testing ECHO – Mississippi – 5-25-2021 – Slides

Lung Cancer Biomarker Testing ECHO – Session 0 – Resources

Understanding the Barriers to Biomarker Testing

This session will provide an overview of the biomarker continuum through the lens of the critical medical stakeholders, showcasing the coordinated sequence of events that is required and the common gaps at every stage of the multidisciplinary care continuum.

Didactic Presenter

M. Patricia Rivera, MD

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Lung Cancer Biomarker Testing ECHO – 6-28-2021 – Case Presentation

Lung Cancer Biomarker Testing ECHO – 6-28-2021 – Recording

Lung Cancer Biomarker Testing ECHO – 6-28-2021 – Slides

Lung Cancer Biomarker Testing ECHO – Session 1 – Resources

Pathways to Biomarker Testing (Patient Lens)

This session will provide an overview of the pathways to biomarker testing, through the lens of the patient, especially emphasizing the steps, the process, and the length of time involved.

Didactic Presenters

Raymond Osarogiagbon, MBBS, FACP

Suresh Ramalingam, MD, FASCO

Ralph Zinner, MD

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Lung Cancer Biomarker Testing ECHO – Georgia – 7-21-2021 – Case Presentation

Lung Cancer Biomarker Testing ECHO – Georgia – 7-21-2021 – Recording

Lung Cancer Biomarker Testing ECHO – Georgia – 7-21-2021 – Slides

Lung Cancer Biomarker Testing ECHO – Kentucky – 8-9-2021 – Case Presentation

Lung Cancer Biomarker Testing ECHO – Kentucky – 8-9-2021 – Recording

Lung Cancer Biomarker Testing ECHO – Kentucky – 8-9-2021 – Slides

Lung Cancer Biomarker Testing ECHO – Mississippi – 7-27-2021 – Case Presentation

Lung Cancer Biomarker Testing ECHO – Mississippi – 7-27-2021 – Recording

Lung Cancer Biomarker Testing ECHO – Mississippi – 7-27-2021 – Slides

Lung Cancer Biomarker Testing ECHO – Session 2 – Resources

Adequate Tissue for Sampling

This session will define the overall role of the multidisciplinary care team, including the coordination by pathologists and medical oncologists to ensure adequate lung cancer tissue is collected for testing. Additionally, it will provide guidance on how to procure adequate tissue samples that allow for accurate characterization of histology, biomarker testing, and the tissue and discuss the approaches of the different proceduralists.

Didactic Presenter

Gerard Silvestri, MD, MS, FCCP

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Lung Cancer Biomarker Testing ECHO – 8-26-2021 – Case Presentation

Lung Cancer Biomarker Testing ECHO – 8-26-2021 – Slides

Lung Cancer Biomarker Testing ECHO – 8-26-2021 – Recording

Lung Cancer Biomarker Testing ECHO – Session 3 – Resources

Choice of Panel, Interpretation of Results, and Next Steps

This session will provide guidance and recommendations regarding the appropriate biomarker testing modalities (next-generation sequencing (NGS), Fluorescence in situ hybridization (FISH), and blood. Additionally, it will discuss how to interpret the current NGS reports and the appropriate next steps, e.g. recommendations for FDA approved treatments or cancer clinical trials (if no FDA approved treatment exists, etc.).

Didactic Presenter

Ignacio Wistuba, MD

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Lung Cancer Biomarker Testing ECHO – 9-23-2021 – Case Presentation

Lung Cancer Biomarker Testing ECHO – 9-23-2021 – Slides

Lung Cancer Biomarker Testing ECHO – 9-23-2021 – Recording

Lung Cancer Biomarker Testing ECHO – Session 4 – Resources

Improving Turnaround Time

This session will offer strategies to reduce turnaround time and present approaches to help ameliorate the patient’s wait time for the results.

Didactic Presenter

Lynette Sholl, MD, FCAP

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Lung Cancer Biomarker Testing ECHO – 10-19-2021 – Case Presentation

Lung Cancer Biomarker Testing ECHO – 10-19-2021 – Slides

Lung Cancer Biomarker Testing ECHO – 10-19-2021 – Recording

Georgia- Navigating Insurance Complexities

This session will explore the current coverage policies and reimbursement for single gene tests, as compared to multi-gene panel tests by private and public payers in each state and provide solutions to overcome reimbursement barriers.

Didactic Presenters

Nagla Abdel Karim, MD

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Lung Cancer Biomarker Testing ECHO – Georgia – 11-10-2021 – Case Presentation

Lung Cancer Biomarker Testing ECHO – Georgia – 11-10-2021 – Slides

Lung Cancer Biomarker Testing ECHO – Georgia – 11-10-2021 – Recording

Kentucky - Understanding the Payers Perspective an How to Get Approval

Didactic Presenters

Mark D. Birdwhistell, MPA

Samantha M. O’Bryan

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Lung Cancer Biomarker Testing ECHO – Kentucky – 11-4-2021 – Case Presentation

Lung Cancer Biomarker Testing ECHO – Kentucky – 11-4-2021 – Slides

Lung Cancer Biomarker Testing ECHO – Kentucky – 11-4-2021 – Recording

Mississippi - Navigating Insurance Complexities

Didactic Presenters

Kelly Mrachek, MD

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Lung Cancer Biomarker Testing ECHO – Mississippi – 11-30-2021 – Case Presentation

Lung Cancer Biomarker Testing ECHO – Mississippi – 11-30-2021 – Slides

Lung Cancer Biomarker Testing ECHO – Mississippi – 11-30-2021 – Recording

Lung Cancer Biomarker Testing ECHO – Session 5– Resources

Georgia- Biomarker Testing for Lung cancer: Today and Tomorrow

Didactic Presenters

Suresh Ramalingam, MD, FASCO

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Lung Cancer Biomarker Testing ECHO – Georgia – 2-23-2022 – Slides

Lung Cancer Biomarker Testing ECHO – Georgia – 2-23-2022 – Recording

Kentucky - The Role of the Molecular Tumor Board

Didactic Presenters

Jill Kolesar, PharmD, MS, BCPS, FCCP

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Lung Cancer Biomarker Testing ECHO – Kentucky – 12-2-2021 – Recording

Lung Cancer Biomarker Testing ECHO – Kentucky – 12-2-2021 – Slides

Mississippi - What’s new in Biomarkers Driven Lung Cancer Care in 2021

Didactic Presenters

Pierre De Delva, MD

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Lung Cancer Biomarker Testing ECHO – Mississippi – 1-25-2022 – Slides

Lung Cancer Biomarker Testing ECHO – Mississippi – 1-25-2022 – Recording

Our Experts

Susanne Arnold, MD

Associate Director of Clinical Translation

University of Kentucky Markey Cancer Center

Pierre De Delva, MD

Section Chief of General Thoracic Surgery

Associate Program Director, Cardiothoracic Fellowship Program

University of Mississippi Medical Center Cancer Center and Research Institute

Farhood Farjah, MD, MPH, FACS

Associate Professor of Surgery

Endowed Chair in Lung Cancer Research

Associate Medical Director for the Surgical Outcomes Research Center

University of Washington

Eric Flenaugh, MD, FCCP

Director of Advanced Diagnostic Interventional Pulmonary Medicine

Lung Nodule Clinic Physician Director

Grady Health System

Zhonglin Hao, MD, PHD

Professor of Medicine and Cancer Biology and Medical Director

University of Kentucky Markey Cancer Center

Bruce Johnson, MD, FASCO

Chief Clinical Research Officer at Dana-Farber/Harvard Cancer Center

Past-President of the American Society of Clinical Oncology

Adam Jones, MD

Radiation Oncology at Phoebe Putney Health System

Chair of the Georgia Lung Cancer Roundtable

Jill Kolesar, PharmD, MS, BCPS, FCCP

Director of the Precision Medicine Center, Co-Chair of the Molecular Tumor Board, and
Co-Leader of the Developmental Therapeutics Program

University of Kentucky Markey Cancer Center

Timothy Mullett, MD, MBA, FAC

Medical Director, Markey Cancer Center Network Development

University of Kentucky Markey Cancer Center

Raymond Osarogiagbon, MBBS, FACP

Director, Multidisciplinary Thoracic Oncology Program

Baptist Cancer Center

Shadi Qasem, MD, MBA

Associate Professor and Director of Surgical Pathology

University of Kentucky Markey Cancer Center

Suresh Ramalingam, MD, FASCO

Deputy Director, Winship Cancer Institute

Professor, Department of Hematology and Medical Oncology

Roberto C. Goizueta Distinguished Chair for Cancer Research

Director, Lung Cancer Program

Winship Cancer Institute at Emory University

M. Patricia Rivera, MD

Professor of Medicine at University of North Carolina at Chapel Hill

Secretary-Treasurer at the American Thoracic Society

Michal Senitko, MD, DAABIP

Section Chief, Interventional Pulmonology and Assistant Professor of Medicine and Surgery at the University of Mississippi Medical Center

Co-Director Lung Cancer Screening Program at UMMC Cancer Center and Research Institute

Lynette Sholl, MD, FCAP

Associate Professor of Pathology

Dana-Farber/Harvard Cancer Center

Gerard Silvestri, MD, MS, FCCP

Hillenbrand Professor of Thoracic Oncology at Medical University of South Carolina

Immediate Past President of the American College of Chest Physicians

Robert Smith, PhD, FSBI

Senior Vice President, Cancer Screening

American Cancer Society

John Villano, MD, PHD

Director, Clinical Neuro-Oncology Research Program

University of Kentucky Markey Cancer Center

Ignacio Wistuba, MD

Division Head and interim, Division of Pathology/Lab Medicine Professor

Chair, Department of Translational Molecular Pathology, Division of Pathology/Lab Medicine

The University of Texas MD Anderson Cancer Center

Ralph Zinner, MD

Director of the Thoracic Oncology Program

University of Kentucky Markey Cancer Center

Nagla Abdel Karim, MD

Director, Thoracic Oncology Program

Augusta University Georgia Cancer Center

Mark D. Birdwhistell, MPA

Vice President, Health System Administration & Chief of Staff

University of Kentucky HealthCare

Samantha M. O’Bryan

Practice Manager

University of Kentucky Markey Cancer Center

Kelly Mrachek, MD

Assistant Professor of Pathology

University of Mississippi Medical Center

Collected Program Resources