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Lung Cancer Biomarker Testing ECHO Year 3

December 2023

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May 2024

Introduction to ECHO and Biomarker Testing Guidelines Overview

This session provided an overview of the ECHO model, along with providing a data level-set of the current burden of lung cancer in each state, and provide a brief introduction to lung cancer biomarker testing, including the current guidelines and approved FDA biomarker-driven treatments.

Didactic Presenter

DuyKhanh Pham “Mimi” Ceppa, MD, FACS

Aakash Desai, MBBS, MPH

Understanding the Barriers and Pathways to Lung Cancer Biomarker Testing

This session will provide an overview of the biomarker continuum through the lens of the critical medical stakeholders, showcasing the coordinated sequence of events that is required and the common gaps at every stage of the multidisciplinary care continuum.

Didactic Presenter

Millie Das, MD

Adequate Tissue for Sampling

This session will define the overall role of the multidisciplinary care team, including the coordination by pathologists and medical oncologists to ensure adequate lung cancer tissue is collected for testing. Additionally, it will provide guidance on how to procure adequate tissue samples that allow for accurate characterization of histology, biomarker testing, and the tissue and discuss the approaches of the different proceduralists.

Didactic Presenter

Nichole T. Tanner, MD, MSCR

Choice of Panel, Interpretation of Results, and Next Steps

This session will provide guidance and recommendations regarding the appropriate biomarker testing modalities (next-generation sequencing (NGS), Fluorescence in situ hybridization (FISH), and blood. Additionally, it will discuss how to interpret the current NGS reports and the appropriate next steps, e.g. recommendations for FDA approved treatments or cancer clinical trials (if no FDA approved treatment exists, etc.).

Didactic Presenter

Ignacio Wistuba, MD

Improving Turnaround Time

This session will offer strategies to reduce turnaround time and present approaches to help ameliorate the patient’s wait time for the results.

Didactic Presenter

Jason Merker, MD, PhD

Navigating Insurance Challenges

This session will explore the current coverage policies and reimbursement for single gene tests, as compared to multi-gene panel tests by private and public payers in each state and provide solutions to overcome reimbursement barriers.

Series Wrap Up and Next Steps

Our Experts

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Bruce Johnson, MD, FASCO

Professor of Medicine, Harvard Medical School

Senior Advisor to the President,

 

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Timothy Mullett, MD, MBA, FACS

Medical Director, Markey Cancer Center Network Development

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Millie Das, MD

Chief, Oncology

VA Palo Alto Health Care System

Clinical Associate Professor

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Aakash Desai, MBBS, MPH

Assistant Professor Of Medicine

O’Neal Cancer Center

 

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Grace Dy, MD

Professor of Oncology

 

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DuyKhanh Pham “Mimi” Ceppa, MD, FACS

Associate Professor of Thoracic Surgery

 

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Matthew Facktor, MD

System Chief, Thoracic Surgery

 

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Adam Fox, MD

Assistant Professor

 

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Jason Merker, MD, PhD

Associate Professor, Department of Pathology and Laboratory Medicine & Genetics

University of North Carolina

 

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Koosha Paydary, MD, MPH, MSc

Assistant Professor, Department of Internal Medicine

 

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Catherine R. Sears, MD

Associate Professor of Medicine, Division of Pulmonary, Critical Care, Sleep and Occupational Medicine

Indiana University School of Medicine

 

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Michal Senitko, MD

Assistant Professor

 

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Gerard Silvestri, MD, MS

Hillenbrand Professor of Thoracic Oncology

 

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Heather Wakelee, MD

Professor of Medicine and Chief of the Division of Oncology, Stanford University School of Medicine

Deputy Director,

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Ignacio Wistuba, MD

Professor and Chair, Department of Translational Pathology

 

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Nichole T. Tanner, MD, MSCR

Professor of Medicine

 

Collected Program Resources

Financial Support Provided By

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